Do not delay treatment with antidote more than 8 hours following the ingestion of acetaminophen.Do not use activated charcoal after 4 hours of acetaminophen ingestion.Do not overlook acetaminophen in those who have signs suggestive of overdose with other agents. Consider liver transplantation if the patient has liver failure and meets the criteria for transplantation.If acetaminophen level can not be obtained, assume that that patient has overdose of acetaminophen and treat with N-acetylcysteine.
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